Several mitochondrial dysfunctions have been linked with multiple human diseases, making mitochondria a crucial pharmacological target for the treatment of a broad range of diseases.
One of the key tools in studying mitochondria is MitoTracker™ Green, a green-fluorescent mitochondrial stain that localizes to mitochondria of live cells.MitoTracker™ Green offers a wide range of applications in cellular analysis. It allows for the analysis of cell structure, tracing, tracking, cellular imaging, immunofluorescence staining and detection, mitochondria function, mitochondrial structure, and organelle tracing.
With its ability to specifically target mitochondria, researchers can gain valuable insights into the health and functionality of these vital cellular powerhouses. To demonstrate the effectiveness of MitoTracker™ Green, we conducted experiments comparing its staining efficacy with our innovative SPAchip® technology and another commercial dye. The results were astounding. When cells were incubated with the commercial dye, the MitoTracker™ Green staining intensity decreased at both 24 and 48 hours after treatment. This decrease in fluorescence intensity suggests a decline in mitochondrial health.
The revolution is coming using SPAchip® technology. The cells incubated with our CytoCHECK SPAchip® kits displayed a fluorescence intensity similar to the control group, indicating fully healthy mitochondrial structures. These findings highlight the power of using MitoTracker™ Green in conjunction with our SPAchip® technology. By combining these two cutting-edge tools, researchers can accurately assess mitochondrial health and gain a deeper understanding of the impact of various treatments or interventions on these crucial cellular components. The ability to visualize and track mitochondria using both technologies together opens up new avenues for studying mitochondrial dysfunction and developing targeted therapies for associated diseases. Whether it’s analyzing changes in mitochondrial structure, tracking mitochondrial movement, or assessing mitochondrial function, they provide researchers with a powerful tool to unravel the mysteries of these vital cellular organelles.
In conclusion, the combination of these powerful tools is a game-changer in the field of mitochondrial research.
The MitoTracker™ Green ability to stain live cell mitochondria and its compatibility with our innovative SPAchip® technology make it an indispensable tool for researchers looking to delve deeper into mitochondrial health and its implications in various diseases.
Need more information?
Contact with our Senior Scientist at CRO Unit Services