Cell-based Assay services

Imagine you could keep an eye inside a living single cell and be able to know what is happening at every moment…

An understanding of cell biology should include seeing cellular phenotypes in their intact state (by using SPAchip® in combination with image analysis) and communicating these through quantitative analysis whenever possible, but the understanding of cell biology must begin at the beginning.

With A4cell’s SPAchip® assay services, your cell studies will be enhanced by our SPAchip expertise, our cell assay knowledge, and our latest single-cell analysis equipment. Now, intracellular activity can be analysed in vivo with unprecedented detail.

Our work proccess:

Cell Assay design

  • Cell type selection
  • Tratment & assay conditions

Cell-based Assay & live cell imaging

  • Spachip assays (pH & calcium)
  • Live and death (viability)
  • Cytotoxicity
  • Apoptosis
  • Cell health monitoring for QC
  • Ion channel screening (calcium) conditions

Data Analysis

  • Image analysis (image, cell profiler, harmony)
  • Results (raw images & data)

End report

  • Full report and interpretation

Applications:

ONCOLOGY

  • Cell proliferation
  • Apoptosis
  • Cell migration
  • Tumor Microenvironment
  • Inmuno oncology
  • Ferroptosis
  • Inflammation

METABOLISM

  • Oxidative
  • Mitochondrial function
  • Acidification
  • Calcium signaling
  • Glucose consumption
  • Response to hypoxia
  • Autophagy

iPS CELL

  • Cell culture quality control
  • Differentation processesz

CELL THERAPY

  • Cell culture quality control
  • Viability and proliferation
  • Cell functional properties

CARDIOVASCULAR

  • Mitochondrial function
  • Acidification
  • Calcium signaling
  • Glucose consumption
  • Response to hypoxia
  • Autophagia

NEUROSCIENCE

  • Neurodegenerative Disease
  • Synaptic function
  • Calcium signaling
  • Neural development
  • Electrophysiology
  • Metabolism

SPAchip® Imaging and
Assay Capabilities

  • High-content imaging system
  • Flow cytometer
  • Safety Cabinet
  • Fluorecence Microscopy
  • CO2 Incubator
  • Centrifuge
  • Thermostatic bath
  • Freezer and nitrogen storage tank
  • Data treatment software

Contact Us!

We are your perfect CRO partner for cell assays based on SPAchip® devices.

Let´s work together and see how we can help you with your research!

Marina Martinez Senior Scientist

Like an eye
in the cell!

What would you use SPAchip® technology for?

Tell us and help understanding and developing our product