Welcome to A4liveCell Blog #3! SPAchip® technology enables the study of calcium signaling in receptor pharmacology. Calcium ions (Ca2+) are one of the most important signal transducers in cells, hence intracellular levels must be tightly regulated since prolonged high levels can lead to cell death. Since extracellular calcium concentration is usually 20,000-fold higher than intracellular […]
Work Site: Pozuelo de Alarcon. Madrid (SPA) About the Role: We are seeking a Data Image Analyst with expertise in High Content Screening (HCS) Techniques and Live Cell Imaging Software. This is an exceptional opportunity for a skilled professional to join our dynamic team and play a crucial role in advancing our innovative projects. Key […]
In the dynamic landscape of drug discovery, precision is paramount. High content screening (HCS) assays serve as indispensable tools, providing invaluable insights into cellular responses to various compounds. Yet, amidst the complexity of experimental design, two crucial factors often overshadowed are drug redosing and confluence levels, both wielding significant influence over assay outcomes. Drug Redosing: […]
Welcome to A4liveCell Blog #2! Unlocking Cellular Secrets with CytoCHECK SPAchip® In this edition of our blog, we’re excited to spotlight the transformative CytoCHECK SPAchip® technology, particularly focusing on our cutting-edge pH and Calcium multi-detection kits. These tools are not merely additions to the cell researcher’s toolkit; they represent a paradigm shift in how we […]
Welcome to the first A4 liveCell Blog! In this edition, we delve into the crucial aspects of cell studies Our focus today is on the innovative CytoCHECK SPAchip® pH detection kits, a game-changer in the field of cell research.In cell studies, maintaining optimal pH levels is not just important; it’s a necessity. Why, you ask? […]
The power of multiplexed live analytics in cell biology Cells are continuously challenged by insults and stimuli, including drugs and xenobiotics, from the extracellular environment. In response to these challenges, a series of intracellular molecules and ions act as signalling mediators, effectors or transducers which will ultimately result into physiological changes. In this context, noteworthy […]
A4cell is thrilled to mark the culmination of an exhilarating year with a significant milestone – the acquisition of a substantial €3 million investment. This momentous investment will serve as the catalyst for revolutionizing the landscape of living single cell analysis. The investment will primarily be channeled towards intensifying research and development efforts, expanding our […]
Several mitochondrial dysfunctions have been linked with multiple human diseases, making mitochondria a crucial pharmacological target for the treatment of a broad range of diseases. With its ability to specifically target mitochondria, researchers can gain valuable insights into the health and functionality of these vital cellular powerhouses. Mitochondrial stainings localize mitochondria of live cells and […]
Several mitochondrial dysfunctions have been linked with multiple human diseases, making mitochondria a crucial pharmacological target for the treatment of a broad range of diseases. One of the key tools in studying mitochondria is MitoTracker™ Green, a green-fluorescent mitochondrial stain that localizes to mitochondria of live cells.MitoTracker™ Green offers a wide range of applications in […]
Have you ever wondered if you could find answers from a single cell? Well, in the rapidly evolving field of living single-cell analysis, the possibilities are endless. The study of cellular biology and its implications for health and disease continues to develop innovative methods, and it is the small things that hold the key to […]
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