A4cell has already expanded its portfolio of available wavelengths for the SPAchip® kits with the new CytoCHECK SPAchip® pH RED single-detection kit. This novel product allows working in longer wavelengths that reduce phototoxicity and interference of autofluorescent cell signals. Its ratiometric behaviour at two different emission wavelengths offers increased precision for intracellular pH measurements, while […]
Go in! Discover A4cell April News
April Newsletter is here! Go in March newsletter and… Discover SPAchip® technology can be used as alternative method to animal testing in drug development and other areas of biomedical research biological processes.. Learn how our Service Unit work Come with us to next events We hope you will join us in our journey as we […]
Animal care, FDAMA, & spheroid model with SPAchip® technology
April is a month dedicated to raising awareness about animal abuse and promoting animal welfare. One area where this topic is particularly relevant is biomedical research, where animals are often used to test new treatments and drugs. However, lately, there has been a growing movement towards reducing the use of animals in this field. The […]
Go in! Discover A4cell March News
March Newsletter is here! Go in March newsletter and… Learn about how high-content assays have become a valuable tool for studying a wide range of biological processes.. Meet our new exclusive distributors and team. Discover the therapeutic areas in living single cell valid for SPAchip® applications Come with us to next events We hope you […]
What is wrong with this image?
High-content assays can exhibit varying levels of complexity, but the advent of automated microscopy has created new opportunities for investigating a wide range of phenotypes. Image-based assays have proven useful in addressing numerous questions pertaining to cell biology. By utilizing microscopy-based screens, it is possible to accurately measure phenotypes in individual cells and analyze heterogeneous […]
Expanding presence in Europe!
n Our warmest welcome to Proteigene and Thistle Scientific as our new exclusive distributor in Europe With the signing of distribution agreements with Proteigene and Thistle Scientific Ltd, we expand our presence in France and UK markets. Proteigene is a company that specializes in providing products and services in the fields of Cell Biology, Genomics, […]
Go in! Discover A4cell February News
n February Newsletter is here! Go in February newsletter and… Learn about how CytoCHECK SPAchip® pH single-detection kits have been designed to monitor intracellular pH changes in living single cells, providing a valuable tool for researchers studying cell physiology, metabolism, and proliferation. Join A4cell at SLAS 2023 conference in San Diego from February 25th to […]
Go in! Discover A4cell January News
Our first Newsletter of the year is here! Welcome to the first newsletter of the year! We have set important goals for the year ahead and we are excited to share some of them with you. One of our main goals this year is to improve the efficiency of our cell assays. We understand the […]
Truly Effective Cell Assay Design
The Assay Guidance Manual is a guide for researchers working in preclinical stages of drug development and basic cell biology. The manual is an updated review of all critical aspects for design, development and optimization for in vitro and in vivo assays used to validate a drug [1]. The design of effective and reliable protocols […]
Lab-in-a-cell analysis enabled by SPAchip® Technology
About Probes for analyzing intracellular signaling activities have been indispensable tools for understanding cell biology in the last decades. Yet, novel approaches have allowed to overcome technological limitations in each generation and to improve the quality of the obtained data in cell-based assays. The latest developments in physico-chemical procedures enable to perform real-time assays in […]